June 6, 2018
The Endometrial Scratch trial is a randomised controlled trial aiming to assess the effectiveness of local endometrial trauma (also known as “endometrial scratch”) on In Vitro Fertilisation (IVF).
The use of Endometrial Scratch has not yet been fully tested in women who are about to have IVF/ICSI for the first time, but similar trials have used the same technique in women undergoing IVF/ICSI for the second or subsequent time, with beneficial results.
1044 women will be recruited across the UK to be randomised to either receive the endometrial scratch intervention followed by “usual” IVF, or to just receive “usual” IVF. The pregnancy rates in each group will be analysed to assess if the endometrial scratch has a positive effect.